Section 5: Director of the Institute.

(1) The President shall, on the recommendations of the Minister, appoint a Director of the Institute.
(2) A person shall not be qualified to be appointed as a Director unless the person is an oncologist with 10 years’ research experience and preferably a Professor with administrative experience.
(3) The Board shall not exercise any disciplinary control over the Director without the approval of the Minister.
(4) Subject to the provision of this Act and the control of the Board over the matters affecting finance of the Institute, the Director shall be the Chief Executive of the Institute and shall be charged with the general responsibility for the management and administration of the affairs of the Institute and, in particular-
(a) direct and regulate the programme of work at the Institute;
(b) promote research within and outside the Institute;
(c) keep safe custody of all records of the Institute;
(d) demand and receive, from any person attending training or courses at the Institute, fees as the Board may determine;
(e) prepare and present to the Board annual and other reports on the progress of work at the institute and on the expenditure or liabilities of the Institute;
(f) be responsible for the day-to-day running and management of the Institute;
(g) exercise such powers and discharge such duties as may be determined by the President;
(h) create a central online data base for statistical analysis to create access by both public and private individuals with a view to attracting donor agencies;
(i) establish a department of telemedicine for collaboration with peers both within and outside the country; and
(j) be responsible for establishing a cancer preventive protocol according to age and family history of every Nigerian with a view to carrying out a public awareness campaigns for screening right from the primary health centre to the secondary and tertiary hospitals with the ultimate referral centre for everything cancer being the Institute aimed at eradicating medical tourism by the theme "operation know your health centre and referral point".